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KMID : 0358920000270030400
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Journal of the Korean Academy of Pedodontics
2000 Volume.27 No. 3 p.400 ~ p.409
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Electrophysiological and morphological characteristics of facial mucleus in rat
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Choi Byung-Ju
Cho Jin-Hwa
Bae Yong-Chul
Kim Young-Jin
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Abstract
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This study used in vivo intracellular and extracellular fIeld potential recording to evaluate the intrinsic membrane properties and connection pattern within facial nucleus.
1.There were four subdivisions of medial, intermediate, lateral, and dorsolateral in facial nucleus.
2.Principal cells in the facial nucleus was recorded from and filled with neurobiotin in anesthetized rats. The extent of their dendrites and the characteristics of cell body were examined.
3.Principal cells had a large amplitude action potential and afterhyperpolarization was followed a single action potential.
4.The response from facial motonucleus to electrical stimulation of the facial nerve was mainly a monophasic wave, with a latency of 1 msec, which was assumed to reflect antidromic activation of facial motoneurons. In some of rats the response in addition showed late components at a latency of about 7-8 msec, but its amplitude was small.
5.Mest of cells exhibited accommodation of spike discharge upon depolarization of membrane by 0.8 nA for 400 ms.
Our results support the hypothesis that there normally are weak connections between different parts of the facial motonucleus to explain pathophysiology of hemifacial spasm and facial nerve paralysis.
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KEYWORD
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Facial nucleus, Synapse, Membrane properties, Facial nerve paralysis, Hemifacial spasm
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